TheWellnessLiving Health Tips

Cholesterol: the key to heart disease

In fact, treatment to lower cholesterol in the category of people who have been diagnosed with heart problems who have such symptoms, is extremely beneficial to the health of the individual. Persons who had a heart attack or heart disease are prone to angina pectoris, peripheral arterial problems, abdominal aortic aneurysm or carotid artery disease, or those who had surgery, may be affected 7 times faster than others.

A lot of studies have shown that those already suffering from heart disease are successful in terms of cholesterol-lowering treatment. No matter what method they choose, they will increase their chances of avoiding a heart attack or other diseases.

Indeed, according to a study done in 1999 on the treatment of revascularization suggests that statin-based treatment – used in an aggressive treatment for lowering total LDL – is as effective as angioplasty in helping people to avoid a heart attack, palpitations, sudden stings. In this study, 314 people with diseases of the coronary artery were randomly chosen to make a treatment daily with their medication. After 18 months, those taking statin (inhibitor reducers) no longer needed a surgical intervention.

Following these trials, specialists recommend aggressive treatment for lowering cholesterol for all categories of persons who survived a heart attack, but also those who have LDL levels greater than 100mg/dl. Moreover, experts note that 70mg/dL LDL in people who have heart problems, is not a good. To control cholesterol, besides medicines should follow a healthy lifestyle, which include a diet and exercise.

New researchs revealed that statin therapy has other effects besides lowering cholesterol, such as improving the functioning of blood vessels narrow. Also, other positive effects that statin may be observable over the body after 30 days of treatment.

Despite the records that a treatment to lower cholesterol is safe and effective in people with heart disease, most people who deserve and need to do a treatment, do not do it. This situation arises because some doctors recommend a wrong medicine, and some patients are treated by the ear.

Cardiovascular disease risk factors

The more a person shows several factors, the greater the chances of developing heart disease. The best way to prevent heart attacks is represented by reducing risk factors. Risk that can be controlled and treated:

• High blood pressure (hypertension) disrupts the smooth functioning of the heart, amplifying the state of weakness. Both heart and arteries are prone to strokes. High blood pressure increases the risk of stroke, of atherosclerosis, causing congestive heart failure, atherosclerosis, kidney failure and eye disease. When this pressure is associated with obesity, smoking, cholesterol increases the risk of sudden attack. High blood pressure tends to increase with the age. Men are exposed to greater risks than women. After the age of 55 years men shows similar trends for accelerating blood pressure. Instead, after 75 years, women are more prone to such risks than men. HTA’s are not usually defined by symptoms, is a real silent killer. If you are suspected of hypertension, should pay more attention to your health. Keeping a proper diet, losing weight (when applicable), practicing a sport regularly, avoid salt and following a strict medication from a medical specialist, you can keep blood pressure under control (ie lower blood pressure to normal levels), decreasing the worsening condition health;

• Hypercholesterolemia (high levels of blood cholesterol) – coronary heart disease risk increases as you achieve a high cholesterol. When present and other risk factors such as hypertension and smoking, exposure from cardiovascular disease is even greater. Cholesterol is found only in animal fats. Some herbal oil, often used in cooking, are high in saturated fats. Transfats results by adding hydrogen to vegetable oils are often used in restaurants and fast foods. Fruits and vegetables contain no cholesterol, are therefore recommended in any diet. If you need medicines to lower cholesterol is better to resort to a healthy diet reduce the amount of cholesterol and improve your cardiovascular health;

Reversal of type 2 diabetes mellitus and improvements in cardiovascular risk factors after surgical weight loss in adolescents. Pediatrics. 2009 Jan;123(1):214-22 Authors: Inge TH, Miyano G, Bean J, Helmrath M, Courcoulas A, Harmon CM, Chen MK, Wilson K, Daniels SR, Garcia VF, Brandt ML, Dolan LM OBJECTIVES: Type 2 diabetes mellitus is associated with obesity, dyslipidemia, and hypertension, all well-known risk factors for cardiovascular disease. Surgical weight loss has resulted in a marked reduction of these risk factors in adults. We hypothesized that gastric bypass would improve parameters of metabolic dysfunction and cardiovascular risk in adolescents with type 2 diabetes mellitus. PATIENTS AND METHODS: Eleven adolescents who underwent Roux-en-Y gastric bypass at 5 centers were included. Anthropometric, hemodynamic, and biochemical measures and surgical complications were analyzed. Similar measures from 67 adolescents with type 2 diabetes mellitus who were treated medically for 1 year were also analyzed. RESULTS: Adolescents who underwent Roux-en-Y gastric bypass were extremely obese (mean BMI of 50 +/- 5.9 kg/m(2)) with numerous cardiovascular risk factors. After surgery there was evidence of remission of type 2 diabetes mellitus in all but 1 patient. Significant improvements in BMI (-34%), fasting blood glucose (-41%), fasting insulin concentrations (-81%), hemoglobin A1c levels (7.3%-5.6%), and insulin sensitivity were also seen. There were significant improvements in serum lipid levels and blood pressure. In comparison, adolescents with type 2 diabetes mellitus who were followed during 1 year of medical treatment demonstrated stable body weight (baseline BMI: 35 +/- 7.3 kg/m(2); 1-year BMI: 34.9 +/- 7.2 kg/m(2)) and no significant change in blood pressure or in diabetic medication use. Medically managed patients had significantly improved hemoglobin A1c levels over 1 year (baseline: 7.85% +/- 2.3%; 1 year: 7.1% +/- 2%). CONCLUSIONS: Extremely obese diabetic adolescents experience significant weight loss and remission of type 2 diabetes mellitus after Roux-en-Y gastric bypass. Improvements in insulin resistance, beta-cell function, and cardiovascular risk factors support Roux-en-Y gastric bypass as an intervention that improves the health of these adolescents. Although the long-term efficacy of Roux-en-Y gastric bypass is not known, these findings suggest that Roux-en-Y gastric bypass is an effective option for the treatment of extremely obese adolescents with type 2 diabetes mellitus. PMID: 19117885 [PubMed - indexed for MEDLINE]

Resveratrol, obesity and diabetes. Eur J Pharmacol. 2010 Jun 10;635(1-3):1-8 Authors: Szkudelska K, Szkudelski T Resveratrol belongs to the large group of biologically active substances found in plants. This compound is classified as phytoestrogen because of its ability to interact with estrogen receptor. Numerous beneficial effects of resveratrol described in the literature involve cardioprotective, anti-cancer, anti-inflammatory and antioxidant action. Recently, this broad spectrum of effects is enlarged by new data demonstrating a great potency of this compound in relation to obesity and diabetes. It is well established that resveratrol exerts beneficial effects in rodents fed a high-calorie diet. In some studies, resveratrol was reported to reduce body weight and adiposity in obese animals. The action of this compound involves favourable changes in gene expressions and in enzyme activities. The accumulating evidence also indicates the benefits of resveratrol in diabetes and diabetic complications. It is known that resveratrol affects insulin secretion and blood insulin concentration. In animals with hyperinsulinemia, resveratrol was found to reduce blood insulin. Moreover, numerous data indicate that in diabetic rats, resveratrol is able to reduce hyperglycemia. The mechanism of resveratrol's action is complex and is demonstrated to involve both insulin-dependent and insulin-independent effects. These data point to the potential possibility of use of resveratrol in preventing and/or treating both obesity and diabetes.

Anti-atherogenic effects of resveratrol. Eur J Clin Nutr. 2010 Jul;64(7):660-8 Authors: Ramprasath VR, Jones PJ Resveratrol (RS), a polyphenol compound found in grapes and grape products, including wine, peanuts and berries, exists in cis- and trans-isomeric forms. RS is believed to decrease circulating low-density lipoprotein cholesterol levels and reduce cardiovascular disease (CVD) risk. However, it is possible that RS has other mechanisms to reduce the risk of CVD without altering lipid levels. The objective of this review is to critically examine results from recent research concerning potential effects of RS on CVD. RS exerts several health benefits including anti-atherogenic, anti-inflammatory and anti-cancer effects. RS may also prevent lipid oxidation, platelet aggregation, arterial vasodilation and modulates the levels of lipids and lipoproteins. As a potent, anti-oxidant RS reduces oxidative stress and regenerates alpha-tocopherol, which further strengthens the anti-oxidant defense mechanism. RS has been considered safe as no significant toxic effects have been identified, even when consumed at higher concentrations. This evidence identified RS as an effective anti-atherogenic agent, which could be used in the prevention and treatment of CVD. PMID: 20485301 [PubMed - in process]